Computer Running Slow - ComboFix Log Enclosed

Hello. First, I want to thank you in advance for your help. I really do appreciate you taking the time to try and help me with my problem.

I have used Spybot S&D as well as Ad-Aware to disinfect my computer as best as possible. Then I used ComboFix and received a log file. I will paste the log below.

My main problem is that my computer is running significantly slower than usual. I don't really understand why. It takes time for programs to open and load, but typically, once they are open, they run smoothly. I have used the Disk Defragmenter tool, as well as the Disk Cleanup tool, but to no avail has it helped.

Thank you again...My log is below: