posssible malware / virus help

hey guys either by my own ignorance or by some other nasties i think iv got a problem with the household computer , for now i will be using my laptop for the cleaning .

story
household computer protected with nod 32 av , zonealarm fw , ccleaner , spybot s&d , a-squared

i would be the only user with relative computer knowledge , the main users wanted there only user profiles so i began to move files etc, by using the start-up editing function in ccleaner i deleted the path for msm messenger which poped up on start up.to the best of my knowledge this is the only thing that could have triggered the following event

around this period of time i noticed that the system tray was only displaying the sounf properties icon and nothing else , i check the security centre and it says im ok with active firewall and av , do an on-demand scan with nod and it says im ok ,

pass one day of users visiting sites like bebo.com,ufc.com etc

comp now beginning to slow and still no warning from the s/centre of any problems , run a spybot scan and massive amounts of crapware returned begin to get suspicous , block all internet traffic using firewall and close firefox

note: i do a ccleaner scan and it gives me a warning to close firefox but to my knowlege it is ???

run a full system scan using nod 32 and a massive amount of files are returned on the scan with the following after

error opening file [file locked][4]

some examles of the errors found sre as follows

C;\documents and settings\user name\ntuser.dat
C;\documents and settings\localservicentuser.dat
C;\documents and settings\networkservice\ntuser.dat
C;\system volume information\mountpointmanagerremotedatebase
C;\WINDOWS\system32\config\default
C;\WINDOWS\system32\config\default.log
C;\WINDOWS\system32\config\sam
C;\WINDOWS\system32\config\security

during all of this the only pop up coming from the system tray was from nod saying

"some of the suspicious files suitable for analysis have not been approved for sending. To open a confirmation window cllick on this message."

then when i click on it nothing happens anf it just pops up a few mins later

just wondering should i start the malware removal proceudure or not , willl it work and has anybody any insght into what this may be

once again thanks to anyone of assistance

 

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Please follow the instructions in the below link and attach the requested logs when you finish these instructions.

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These files are related to the Windows Registry so it is normal for them to be "locked" during scans because thay are in use by Windows. These files should not be altered in any way.