which s/w malware detection is best to use with Trend Micro Titanium?

Welcome to Major Geeks!

Questions about what is the best malware detection program are very difficult to answer. It can be very subjective and change every month as new updates for software occur and it also changes as new malware comes out. In reality there is no best single piece of software you do need a layered approach to protection as discussed in the below How to Protect yourself from malware! And the most important part of protection is still the end user.

However to more directly answer your question, Trend Micro is a reasonable program. Some people have complained of its inability to remove malware, but that complaint can be made of many commercial antivirus and security suites. And at least one last review did not think too much of Trend Micro ( for example: http://www.av-comparatives.org/images/stories/test/summary/summary2010.pdf ) but the review is from last year but it was not great.

Malwarebytes is not an antivirus program and you only get protection with the paid version. Malwarebytes is a very good antimalware program which is a highly recommended tool to add along side your antivirus and firewall programs.