malware has corrupted installer?

Friend's Windows Vista Home Premium Machine exhibits unusual behavior. Shut down completely and wouldn't boot, I thought it was maybe a bad ac adapter, so I have a Targus device with various ends and I hooked it up and started letting it charge, to see if that was the problem. The battery took a charge really well, so I tried her adapter to see what would happen, and it is working fine as well. I figured I'd go ahead and run all the updates for her just to give it a good look-over, and that's when the fun started. According to the update center, updates haven't been run since sometime in 2009. AFter I ran updates, it still said they haven't been run since that same date in 2009. So I ran the update again, and it failed. Tried again, failed again. Her Norton Internet Security kicked up a message about some malware installed, but her subscription has expired, so it wouldn't do anything about. Going to your Read and Run First, I followed all the steps to get the installers downloaded, did the initial easy-clean (through add/remove programs--not much there). I did install and run SuperAntiSpyware, but it didn't save a log. I think the version is slightly different from when the instructions were written, and the interface is different from what I remember. That is as far as I've gotten.

Malwarebytes won't install. I get a message that says:The filename, directory name, or volume label syntax is incorrect.

Combofix won't run. I get a message that says: NSIS error Error launching installer.

I ran the malwarebytes cleaner, recommended at the malwarebytes website, in case there were things that got started installing wrong, to no avail.

I have run the Windows Installer Clean Up Utility, to no avail.

I have run check disk, to no avail

Any ideas?

And thanks in advance

 

I still couldn't run the programs in safe mode, same error messages. But here are the MGTools logs.