adware and trojan cleaning

good morning... this is my second time posting but not for this... am trying to clean my grandsons laptop that i gave him... i have some questions about putting a few cleaners to the desk top ... i have used them before on my computer ,but when i down load them i only see them as run do i right click to save as and does single clicking make a difference since his is set to do that... one last question ... i look for a reply here or my email address... oh all his infections that i can tell is located in IE/activex-x compatlibitly (registry)

thanks in advance
old_ireland

 

thanks .... i think i understand what ur saying ...but let me make sure combo fix is a file going to the desk top ,not the program files .. am i correct

 

thats what i thought and thanks again for ur help ....i will post there

 

:wave and welcome to MG's..