Cookiies Or Cache issue?

Hi all,
I am at my wits end on this one. It seems like every few days to about a week or so, I have to clear my browsing history and or cache and cookies to view most my my frequented websites. They just will not open at all, or be stuck in loading, or load with everything to the left and words only. My computer is only about 7 months old and it is a 500 GB, 64bit, dual 2.8 processor Asus. I can not figure out what is causing the problem. I should be able to store a boat load of cache and cookies. I have AVG installed at the moment, but have had, Avast and it did not make a difference. I also run windows Advanced systems care every day, right before I shut down. I also run Super Anti-spyware, IOBit and a few others on occasion to try and weed out the problem. Still, it happens especially to G-mail. It will get stuck in loading until I click on basic HTML. But, once I clean and clear everything and restart, I am fine again for a few days. Any thoughts or suggestions. I know my computer is not infected, because I check my it every day and it is still VERY fast. If I am, I never found it.
Kind Regards!
Randy