Erratic Mouse

I'm not sure what kind of issue this may be. I have tried replacing my mouse Marble Logitech with a new wireless Logitech one but the issue is still there.
While playing games on facebook the mouse pointer has shifted(you have to move the pointer around to slightly below or slightly to the side to click what you want-Some games I cannot even open because of this -Its also hard to close game windows since the "X" doesn't work where it should you have to move the mouse around and find the area that works to close it.I am using windowx XP and google Chrome as my browser.
Yesterday I posted on Major Geeks Facebook page and they told me this "Get SlimDrivers from our driver section and update your drivers. Odds are the USB drivers are out of date compared to the mice you are using." I did download it and it said the drivers was out of date I fixed it and rebooted and the issue remains .I posted on the wall 2x's but noone seems to be answering so I came here.
Hope you can guide me in the right direction

 

Any help on this? Direction advice anything? I would really appreciate it-This issue has been going on now for about 2 weeks

 

Sorry about the last posts I didn't see you had replied. here is the information you requested,

Windows service pack #3

its a Marble Mouse - No surface the ball rotates in a socket-Yes i have cleaned it of dust and whatever else gets in there-Not using cleaning stuff just dry paper towel.

Logitech Marble Mouse MN# T-BC 21 it is not wireless. I did purchase a new wireless Logitech mouse MN#M705 (didn't solve the problem) but I would prefer to use the ball

it's a desktop

When I uninstall the mouse drivers and hardware do I need to reboot with mouse disconnected and then plug it in?
Where do I uninstall this from? I looked under add remove programs do not see Logitech or mouse listed there.

 

Windows service pack #3

its a Marble Mouse - No surface the ball rotates in a socket-Yes i have cleaned it of dust and whatever else gets in there-Not using cleaning stuff just dry paper towel.

Logitech Marble Mouse MN# T-BC 21 it is not wireless. I did purchase a new wireless Logitech mouse MN#M705 (didn't solve the problem) but I would prefer to use the ball

it's a desktop

When I uninstall the mouse drivers and hardware do I need to reboot with mouse disconnected and then plug it in?
Where do I uninstall this from? I looked under add remove programs do not see Logitech or mouse listed there.