Event 490 (error) 1032 plz Help!!

Hi hope everyones well ive come up against a little problem ive figured out what it is this is microsofts explanation:-

Error -1032 = 0xfffffbf8 = 4294966264 = JET_errFileAccessDenied = Cannot access file - the file is locked or in use. Another process has "stolen" the file. A virus checker may mistakenly quarantine a file, or a backup process may temporarily deny access. A flat file backup system or anti-virus software may be running against the database, check file directories, or the M: drive. This error can also occur if the permissions on the folder (such as MDBDATA) that contain the files for the information stores are not sufficient for the stores to function properly.

it keeps freezing my pc up and i have to reset this is there sollution:-

For Error -1032, change the permissions on the folders that contain the information store files to the default permissions. Configure the flat file backup and anti-virus software to not to scan the Exchange server information store subdirectories or the M: drive. Use Exchange-aware online backup and anti-virus software.

which brings me to my problem i can't seem to get my head round where to go to do what it say to do :confused :cry can anyone please advise me i would be so greatful :-D

im using AVG antivirus

 

oops sorry and my OS is XP