(non-infection Question) Malwarebytes Msconfig Box Won't Uncheck

I use Malwarebytes for on-demand scanning as needed. I have all the internal program settings turned off so it won't load a start-up or update. But for some reason, when I try to untick the Msconfig box, it simply won't let me. I apply, I restart, it's always there. I even checked services, and it says it's disabled.

This is new behavior for me and this program. Could always do this before. What's blocking it now?

 

Try doing it in Safe Mode.

 

Thanks, but that's the first thing I tried. It's really weird. It's like a springy ball. I click the uncheck and apply and it's like it just bounces right back.

 

Anymore thoughts on what might be tying this up?