Persistent pop-ups...

I'm not sure what you meant by " have tried all the malware/spyware removal programs".

Please follow all the steps in this Sticky thread < READ ME FIRST BEFORE ASKING FOR SUPPORT: Basic Spyware, Trojan And Virus Removal >

If you already have any of the programs linked in the tutorial please double check your version to make sure you have the latest one and that you have any/all updates for the programs.

NOTE: In order to resolve the issues you are having it is very important that you at least try to perform all the steps as outlined. If you have any difficulty please post back letting us know what steps you have completed, what you found while doing the scans if anything and details about any problems you have encountered in completing the steps. The more details you can provide the better.

Also from the Alternate Scans section of the Read Me, run A-squared

 

Did you run A-squared?

You should read the tutorial in this Sticky thread NO HIJACK THIS LOG FILES BEFORE READING THIS: HJT Tutorial & LOG File Posting

Now post a HijackThis as a .txt file attachment to your message. All running programs should be closed, including your web browser, e-mail. Close before running Hijack This!

Do NOT run Hijack This from the Desktop, a temp folder or choose run it directly from the downloaded ZIP file. Place it in its own folder, for example C:\Program Files\HJT

 

You did not run the Symantec online scan. It may have fix at least one of your problems.
I'm working on your log now. I'll be back shortly.

Do you recognize the URL in the below line:
O8 - Extra context menu item: Shorten URL - http://www.cjb.net/menuext.html

 

Make sure you have system restore disabled and viewing of hidden files enabled.

Run HijackThis and select the following lines but DO NOT CLICK FIX until you exit all browser sessions including the one you are reading in right now:
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R3 - Default URLSearchHook is missing
O2 - BHO: Popup Manager - {08E74C67-99A6-45C7-94DA-A397A8FD8082} - (no file)
O2 - BHO: (no name) - {480DF32B-9584-4490-BCB2-F39B59819CEC} - C:\WINDOWS\system32\geb.dll (file missing)
O4 - HKLM\..\Run: [sysu] "C:\progra~1\ddm\sysu.exe"
O4 - Global Startup: Search.vbs
O8 - Extra context menu item: Shorten URL - http://www.cjb.net/menuext.html
O15 - Trusted Zone: *.windupdates.com
Boot into safe mode and use Windows Explorer to delete:
C:\program files\ddm <---- the whole directory
C:\Windows\Search.vbs or C:\Windows\system32\Search.vbs

Right click on your desktop Internet Explorer icon and select Properties. Then click the Programs tab and then click "Reset Web Settings". Now go back to the General tab and set your home page address to something useful like www.majorgeeks.com. Click Apply. Click Delete Cookies, Click Delete Files and select Delete all Offline content too, Click OK. When it finishes Click OK

Now reboot in normal mode and post a new HJT log. And tell us how things are working.

 

Your current log looks okay, but in the future please remember all browsers must be shutdown when running HijackThis to scan and especially when fixing items with HijackThis. You had this running:
C:\Program Files\Internet Explorer\iexplore.exe