Can't start any programs at all, cant use add/remove in control panel.

A virus got into my computer and now I can't run any programs from my desktop shortcuts or their actual start applications in their "Program Files" folders (except firefox (only from corner "Start" button area, not from desktop shortcut)). I can't run any cleaning programs or apps. because I can't unzip anything after it's downloaded. Every time I double click to start a prog a windows dialog box opens with DOS writing. It reads : "Cannot load VDM IPX/SPX support" below that line it reads: "program too big to fit in memory". I can open "control panel" file folder, but when I try to click "add/remove progs" a regular error box opens and reads : "C:\WINDOWS\System32\rundll32.exe" then below that it reads: The parameter is incorrect. What can I do to get programs back running so I can start cleaning process? Thank you

freakthreazy