I have a fairly new HP Desktop PC. I'm running Windows 7 Home 64-bit SP1. Yesterday I noticed that iTunes won't open when I double-click on the shortcut icon on my desktop. I restarted my computer, same issue. I restarted in Safe Mode, same issue. I did not uninstall/reinstall because I also can't open my Spybot-SD. Same thing happens. The process is listed in Task Manager, but the programs just don't open. I have not tried uninstalling/reinstalling the programs because I'm pretty sure it won't help. I tried doing a System Restore back to early February. The System Restore was successful but the problem persists. Also, Windows Media Player opens, but it opens weird, wherein it freezes on a white square for a few minutes before finally loading. Also, my DVD burning software, DVD Flick, opens but first it freezes on a yellow square. It's hard to Google this problem because of all the programs involved, and I'm sure there are more programs that won't open that I'm just not aware of yet. I didn't do anything that I can think of that could've caused the problem (and if I had, the system restore would've fixed it). So I scanned my PC for viruses with Symantec and I also scanned for malware with Microsoft Security Essentials and both scans came up clean. Not being able to use iTunes presents a problem because I can't update my phone or make changes to my phone at all. Any help would be greatly appreciated. Thanks.