Help needed - can't run anything

Try the below steps:
- try using HJT in safe mode
- if that does not work, try renaming hijackthis.exe to myhjt.com and try running that (preferably in normal boot mode)
- if you cannot do the above, run Task Manager and provide a list of running processes.
- always provide your OS in a request for help

 

Is that all the processes? You mean you have no antivirus, no firewall, no spyware blockers running at all.

I assume this Isaas.exe was a typo and you meant lsass.exe


Did you try renaming HJT as suggested? How far do you get when trying to run HJT?

 

If you are using WinXP or WinMe, make sure you have system restore disabled (per the tutorial).
For all OS types, make sure viewing of hidden files is enabled (per the tutorial).

Run HijackThis and select the following lines but DO NOT CLICK FIX until you exit all browser sessions including the one you are reading in right now:
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = res://C:\WINDOWS\system32\shdocsv.dll/API32.htm#ID=347;065D
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = res://shdocsv.dll/asst.htm
O4 - HKLM\..\Run: [intel32.exe] C:\WINDOWS\System32\intel32.exe
O4 - HKLM\..\Run: [Fast Start] C:\WINDOWS\system32\svcnt.exe home
O16 - DPF: {11010101-1001-1111-1000-110112345678} - mkmSItSTORE:Mhtml:FiLE://C:\html.mHT!http://205.177.122.27/docs/xxx/html.chm::/html.exe

After clicking Fix, exit HJT.
Now boot into safe mode (if not already in safe mode) and use Windows Explorer to delete:
C:\WINDOWS\System32\intel32.exe
C:\WINDOWS\system32\svcnt.exe

If you get an error when deleting a file. Right click on the file and check to see if the read only attribute is checked. If it is, uncheck it and try again. Other wise open Task Manager and kill the process if running then delete the file.

Now run Ccleaner (installed while running the READ ME FIRST). Now if running Win XP goto c:\windows\Prefetch and delete all files in this folder.
Now we need to Reset Web Settings:
1) If you have an Internet Explorer icon on your Desktop, goto step 2. If not, skip to step 3.
2) Now right click on your desktop Internet Explorer icon and select Properties. Then click the Programs tab and then click "Reset Web Settings". Now go back to the General tab and set your home page address to something useful like www.majorgeeks.com. Click Apply. Click Delete Cookies, Click Delete Files and select Delete all Offline content too, Click OK. When it finishes Click OK. Then skip step 3.
3) If you do not have an Internet Explorer icon on your Desktop, click Start, Control Panel (for some systems it may be Start, Settings, Control Panel), Internet Options, Programs tab and then click "Reset Web Settings". Now go back to the General tab and set your home page address to something useful like www.majorgeeks.com. Click Apply. Click Delete Cookies, Click Delete Files and select Delete all Offline content too, Click OK. When it finishes Click OK.

Now try to reboot in normal mode and post a new HJT log (even if you have to get one from safe mode again - post it). And tell us how things are working.