Please forgive me if any of this is redundant, I simply am trying to give as detailed of an account as I can. I recently removed a fake trojan "virus" from my PC, it had a window poped up that stated I was infected, via research I discovered that upon clicking it it would scan and present 35 different locations to download a "fix". I got rid of it before that happened, however, there seems to be some nasty side effects still lingering. For a while yesterday I was not able to log onto IE, FireFox, or Google Chrome. I then started looking around the settings and disovered that the "use proxy setting" was ticked, I unticked it and was then able to get back to surfing the internet. Okay, that's the backstory, now the main issue: When I try to run Malwarebytes' Anti-Malware I get: Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access them. When I try to run SUPERAntiSpy, I get the same error message. When I try to run HijackThis, I get the same error message. When I boot up in safe mode, it's the same message. Earlier in the day I was able to get MalwareBytes to run but it would scan for about 3 seconds then close. I use Trend Micro's AntiVirus plus AntiSpyware for daily use, but yesterday it seemed to be trying to do mutilple updates at random times during any give hour. Usually it only checks for updates about once a day. Trying to scan with it shows the time that has elapsed, but it has no current target, which tells me it's not working either. Today it won't even open. Twice yesterday the computer itself crashed to the Blue Screen of Death with a memory dump. Sometimes in the middle of browsing with IE, IE will simply stop responding. After following your steps as listed I am still in need of some help. As best to me knowledge I am running only 1 Anti-virus: Trend Micro's AntiVirus plus Antispyware. I have only 1 firewall. I did the House Cleaning. I tried to update Java to the latest (Java 6 update 22) but first had to delete an older version, Java 6 update 14. It would not let me. When I went in via Add/Remove programs the update/remove button is not there. I can go into CCleaner and click Uninstall but it tells me Error: 5 - Access is denied. I've even looked into the registry for it and it's simply not there. I was looking in: Hkey_local_machine/Software/Microsoft/Windows/CurrentVersion/uninstall Currently I cannot get my Trend Micro to even open, but yesterday I was able to delete all but 5 files from quarantine. I apologize but I do not recall which specific 5 files those were. Recycle Bin is empty. Norton Recycle Bin protection does not apply here. CCleaner ran and did it's cleaning. I am running Windows XP Media Center Edition with SP3. I did not find any Malware via Add/Remove programs. Disabled Disk Emulation via defogger. I am unable to disable spybot's TeaTimer because when I try to open Spybot it tells me: Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access the item. I've downloaded all the programs requested, however, most of the antispyware ones (which I tried to run prior to finding your website) would give me the "Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access the item" error message, which tells me it's not a permission issue, but rather something else preventing me from running it. Attached is the MGlogs.zip as requested.