No sound help

hi. I have absolutely no sound on my laptop. I can't even find the speakers where they are supposed to be.
If I go into sound, speach and audio it says there are no sound devices and al the drop down boxes are greyed out.

I have a Toshiba Equium... I think..

Is this fixable?

Cheers.

 

Thank you, thank you, thank you... thats worked prfectly.

Now I don't suppose you could help with one more thing?

Laptop is running slow and I tried a disk clean up. It goes through the process but doewsn't actualy delete anything. verytime I go back into it its stil got the am amount to clear.