slow performance and runtime error, BSOD

Hi I was asked to post about slow performance. I was working on the Malware side and ran the logs. After review they suggested posting here and the hardware side.
The machine seems to run sometimes then goes wacky. The display updates very slowly almost one line at a time. Selections clicked on take a very long time, 15 seconds or more sometimes. The hard drive light is on almost constantly.
It was noted that I have McAfee and HP programs and that they were high memory items. I have since deleted all HP programs except what is required for my printer.
I got a run time error the last time I shut down. Program C:\Progra~1\McAfee\MSC\MCMSCSVC.exe R6025 pure virtual function call.

I have also had BSOD. Last time i wrote down this IO SYSTEM Verification Error in SDATOR2K.SYS WDM Driver ERRO 216 [SDSTUR2K.SYS+577E@F74E677E.
Not sure what to do now!

 

One posting is fine, thank you.