What would be next step in removal or quarantine of culprit

Computer on network seems to have picked something up again. See other post for other computer. I recently ran CCcleaner, Malwarebytes antihardware and smart defrag. Ringtone ads continue to pop up. Here is the latest posting. What would be the next step.

Malwarebytes' Anti-Malware 1.28
Database version: 1134
Windows 5.1.2600 Service Pack 3

12/7/2008 10:23:09 PM
mbam-log-2008-12-07 (22-23-09).txt

Scan type: Full Scan (C:\|D:\|)
Objects scanned: 96509
Time elapsed: 53 minute(s), 51 second(s)

Memory Processes Infected: 0
Memory Modules Infected: 0
Registry Keys Infected: 2
Registry Values Infected: 1
Registry Data Items Infected: 0
Folders Infected: 0
Files Infected: 1

Memory Processes Infected:
(No malicious items detected)

Memory Modules Infected:
(No malicious items detected)

Registry Keys Infected:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\Browser Helper Objects\{53292177-f6b5-4e66-90b2-bff8f80a44b4} (Trojan.BHO.H) -> Quarantined and deleted successfully.
HKEY_CLASSES_ROOT\CLSID\{53292177-f6b5-4e66-90b2-bff8f80a44b4} (Trojan.BHO.H) -> Quarantined and deleted successfully.

Registry Values Infected:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Run\nawumezubi (Trojan.Agent) -> Quarantined and deleted successfully.

Registry Data Items Infected:
(No malicious items detected)

Folders Infected:
(No malicious items detected)

Files Infected:
C:\WINDOWS\system32\nukiyofi.dll (Trojan.BHO.H) -> Delete on reboot.